CDK inhibitors promote neuroblastoma cell differentiation and increase sensitivity to retinoic acid—a promising combination strategy for therapeutic intervention

Abstract The rarity of recurrent somatic mutations poses a challenge for the targeted treatment of neuroblastoma (NB). Differentiation therapy is an encouraging prospect, with cyclin-dependent kinase inhibitors (CDKis) representing a promising avenue for promoting NB differentiation. This study inve...

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Үндсэн зохиолчид:	Olia Shokraie, Larissa Lechermeier, Pia Bordihn, Philipp Kaps, Steffen Möller, Anna Sophie Schulz, Björn Schneider, Dirk Koczan, Samira Khanipour Roshan, Holger N. Lode, Carl-Friedrich Classen, Olga Hahn, Sascha Troschke-Meurer, Claudia Maletzki
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Publishing Group 2025-08-01
Цуврал:	Cell Death Discovery
Онлайн хандалт:	https://doi.org/10.1038/s41420-025-02637-z
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!