Assessing G4-Binding Ligands In Vitro and in Cellulo Using Dimeric Carbocyanine Dye Displacement Assay

G-quadruplexes (G4) are the most actively studied non-canonical secondary structures formed by contiguous repeats of guanines in DNA or RNA strands. Small molecule mediated targeting of G-quadruplexes has emerged as an attractive tool for visualization and stabilization of these structures inside th...

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Principais autores:	Nakshi Desai, Viraj Shah, Bhaskar Datta
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2021-03-01
Series:	Molecules
Assuntos:	DNA G-quadruplex RNA G-quadruplex G4 ligands fluorescence displacement assay G4 visualization polymerase stop assay
Acceso en liña:	https://www.mdpi.com/1420-3049/26/5/1400
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