Ribosomal Quality Control at the Crossroads of Proteostasis and Diseases: A Guardian and Potential Enabler of Malignant Adaptation

Cancer cells rely on elevated ribosomal biogenesis and protein synthesis to sustain their rapid proliferation. This heightened translational demand imposes significant stress on the fidelity of protein synthesis, thereby necessitating ribosomal quality control (RQC) activation, which safeguards prot...

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Principais autores:	Ishaq Tantray, Rani Ojha
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-03-01
coleção:	Uro
Assuntos:	ribosomal quality control translation ribosomal stalling and collision tumor suppression cancer
Acesso em linha:	https://www.mdpi.com/2673-4397/6/1/8
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