Strategically targeting MYC in cancer [version 1; referees: 2 approved]

MYC is a major driver of cancer cell growth and mediates a transcriptional program spanning cell growth, the cell cycle, metabolism, and cell survival. Many efforts have been made to deliberately target MYC for cancer therapy. A variety of compounds have been generated to inhibit MYC function or sta...

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Principais autores:	Valeriya Posternak, Michael D. Cole
Format:	Artigo
Jezik:	Inglês
Izdano:	F1000 Research Ltd 2016-03-01
Serija:	F1000Research
Teme:	Cancer Therapeutics Cell Growth & Division Cell Signaling Control of Gene Expression Drug Discovery & Design Pharmacogenomics Pharmacokinetics & Drug Delivery Small Molecule Chemistry
Online dostop:	http://f1000research.com/articles/5-408/v1
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