Multi-organ spatial stratification of 3-D dose distributions improves risk prediction of long-term self-reported severe symptoms in oropharyngeal cancer patients receiving radiotherapy: development of a pre-treatment decision support tool

PurposeIdentify Oropharyngeal cancer (OPC) patients at high-risk of developing long-term severe radiation-associated symptoms using dose volume histograms for organs-at-risk, via unsupervised clustering.Material and methodsAll patients were treated using radiation therapy for OPC. Dose-volume histog...

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Autors principals:	Andrew Wentzel, Abdallah S. R. Mohamed, Mohamed A. Naser, Lisanne V. van Dijk, Katherine Hutcheson, Amy M. Moreno, Clifton D. Fuller, Guadalupe Canahuate, G. Elisabeta Marai
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2023-08-01
Col·lecció:	Frontiers in Oncology
Matèries:	radiation therapy clustering head and neck cancer stratification symptom burden quality of life
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1210087/full
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