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Multi-organ spatial stratification of 3-D dose distributions improves risk prediction of long-term self-reported severe symptoms in oropharyngeal cancer patients receiving radiotherapy: development of a pre-treatment decision support tool

PurposeIdentify Oropharyngeal cancer (OPC) patients at high-risk of developing long-term severe radiation-associated symptoms using dose volume histograms for organs-at-risk, via unsupervised clustering.Material and methodsAll patients were treated using radiation therapy for OPC. Dose-volume histog...

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Autori principali: Andrew Wentzel, Abdallah S. R. Mohamed, Mohamed A. Naser, Lisanne V. van Dijk, Katherine Hutcheson, Amy M. Moreno, Clifton D. Fuller, Guadalupe Canahuate, G. Elisabeta Marai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2023-08-01
Serie:Frontiers in Oncology
Soggetti:
radiation therapy
clustering
head and neck cancer
stratification
symptom burden
quality of life
Accesso online:https://www.frontiersin.org/articles/10.3389/fonc.2023.1210087/full
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