The Influenza A Virus H3N2 Triggers the Hypersusceptibility of Airway Inflammatory Response via Activating the lncRNA TUG1/miR-145-5p/NF-κB Pathway in COPD

Background: Patients with chronic obstructive pulmonary disease (COPD) are more susceptible to influenza A virus (IAV) with more severe symptoms, yet the underlying molecular mechanisms of the hypersusceptibility of airway inflammatory response remain unclear.Methods: The primary human bronchial epi...

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Hauptverfasser:	You-Hui Tu, Yan Guo, Shuang Ji, Ji-Long Shen, Guang-He Fei
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2021-02-01
Schriftenreihe:	Frontiers in Pharmacology
Schlagworte:	COPD influenza A virus airway inflammatory hypersusceptibility lncRNA TUG1 miR-145-5p NF-κB
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fphar.2021.604590/full
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