Single T Cell Sequencing Demonstrates the Functional Role of αβ TCR Pairing in Cell Lineage and Antigen Specificity

Although structural studies of individual T cell receptors (TCRs) have revealed important roles for both the α and β chain in directing MHC and antigen recognition, repertoire-level immunogenomic analyses have historically examined the β chain alone. To determine the amount of useful information abo...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Jason A. Carter, Jonathan B. Preall, Kristina Grigaityte, Stephen J. Goldfless, Eric Jeffery, Adrian W. Briggs, Francois Vigneault, Gurinder S. Atwal
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2019-07-01
Serier:	Frontiers in Immunology
Fag:	TCR–T cell receptor CD4 and CD8 T cell repertoires TCR repertoire diversity single-cell sequencing machine learning
Online adgang:	https://www.frontiersin.org/article/10.3389/fimmu.2019.01516/full
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!