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New Oxadiazole/ Benzimidazole Hybrids: Design, Synthesis, and Molecular Docking Studies.

FFive new oxadiazole/benzimidazole hybrids were designed and synthesized as EGFR inhibitors. The structure of the new compounds was confirmed with 1H NMR and 13C NMR as well as elemental analyses. Molecular docking studies were done to investigate their binding mode in ATP binding site of EGFR. The...

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Hlavní autoři: Fatma Hagar, Samar Abbas, Ahmed Sayed, Dalia Abdelhamid, Mohamed Osman
Médium: Artigo
Jazyk:Inglês
Vydáno: Minia University, Faculty of Pharmacy 2023-04-01
Edice:Journal of Advanced Biomedical and Pharmaceutical Sciences
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On-line přístup:https://jabps.journals.ekb.eg/article_290882_c62f3f1f78e8f4761b0ba89b9d401647.pdf
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