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Time-series prediction and detection of potential pathogens in bloodstream infection using mcfDNA sequencing

IntroductionNext-generation sequencing of microbial cell free DNA (mcfDNA-seq) has emerged as a promising diagnostic method for blood stream infection (BSI) and offers the potential to detect pathogens before blood culture. However, its application is limited by a lack of clinical validation.Methods...

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Principais autores: Yinghao Cao, Tingting Jiang, Yanfeng Lin, Xiaofeng Fang, Peipei Ding, Hongbin Song, Peng Li, Yanjun Li
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-05-01
Serier:Frontiers in Cellular and Infection Microbiology
Fag:
microbial cell free DNA
next-generation sequencing
blood stream infection
pathogens
microbiology
Online adgang:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1144625/full
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