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N<sup>6</sup>-Methyladenosine Directly Regulates CD40L Expression in CD4<sup>+</sup> T Lymphocytes

T cell activation is a highly regulated process, modulated via the expression of various immune regulatory proteins including cytokines, surface receptors and co-stimulatory proteins. N<sup>6</sup>-methyladenosine (m<sup>6</sup>A) is an RNA modification that can directly regulate RNA expression leve...

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Main Authors: Ellen C. N. van Vroonhoven, Lucas W. Picavet, Rianne C. Scholman, Noortje A. M. van den Dungen, Michal Mokry, Anouk Evers, Robert J. Lebbink, Jorg J. A. Calis, Sebastiaan J. Vastert, Jorg van Loosdregt
Format: Artigo
Language:Inglês
Published: MDPI AG 2023-07-01
Series:Biology
Subjects:
RNA methylation
epitranscriptomics
CD40 ligand
T cell activation
adaptive immunity
autoimmunity
Online Access:https://www.mdpi.com/2079-7737/12/7/1004
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