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Synthesis and Characterization of Fatty Acid Grafted Chitosan Polymeric Micelles for Improved Gene Delivery of VGF to the Brain through Intranasal Route

Multifunctional fatty acid grafted polymeric micelles are an effective and promising approach for drug and gene delivery to the brain. An alternative approach to bypass the blood–brain barrier is administration through intranasal route. Multifunctional fatty acid grafted polymeric micelles were prep...

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Principais autores: Richard Nii Lante Lamptey, Avinash Gothwal, Riddhi Trivedi, Sanjay Arora, Jagdish Singh
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-02-01
Serier:Biomedicines
Fag:
intranasal
chitosan grafted micelles
blood–brain barrier
transfection
polymer
synthesis
Online adgang:https://www.mdpi.com/2227-9059/10/2/493
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