Regulation of Aldosterone Secretion by Substance P and the Neurokinin Type 1 Receptor in Aldosterone‐Producing Adenomas

Background Aldosterone‐producing adenoma (APA) is a major cause of primary aldosteronism, the most frequent form of secondary hypertension. Although somatic mutations in ion channels within APA have been shown to activate Ca2+ signaling and drive aldosterone production, the pathophysiology of primar...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Antoine‐Guy Lopez, Céline Duparc, Sylvie Renouf, Margot D’Agostino, Kelly De Sousa, Laurence Amar, Guillaume Defortescu, Gilles Manceau, Jean‐Christophe Sabourin, Fabio Luiz Fernandes‐Rosa, Maria‐Christina Zennaro, Tchao Meatchi, Gaël Nicolas, Estelle Louiset, Hervé Lefebvre
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2026-01-01
Schriftenreihe:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Schlagworte:	adenoma adrenal cortex aldosterone neurokinin 1 receptor primary aldosteronism substance P
Online-Zugang:	https://www.ahajournals.org/doi/10.1161/JAHA.125.045539
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