Four-Color Pseudovirus-Based Neutralization Assay: A Rapid Method for Evaluating Neutralizing Antibodies Against Quadrivalent Hand, Foot, and Mouth Disease Vaccine

Background/Objectives: Enterovirus 71 (EV71) and coxsackieviruses A16 (CA16), A10 (CA10), and A6 (CA6) are the primary pathogens that cause hand, foot, and mouth disease (HFMD). Currently, many manufacturers are developing bivalent, trivalent, and tetravalent vaccines that target these antigens. Cel...

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Main Authors: Fan Gao, Lingjie Xu, Qian Wang, Gang Wang, Mingchen Liu, Lu Li, Qian He, Xuanxuan Zhang, Ying Wang, Qunying Mao, Zhenglun Liang, Tao Wang, Xiao Ma, Xing Wu
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2025-03-01
Series:Vaccines
Assuntos:
hand, foot, and mouth disease
enterovirus
quadrivalent vaccine
pseudovirus-based neutralization assay
Acceso en liña:https://www.mdpi.com/2076-393X/13/3/320
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