Alternate Pembrolizumab Dosing Interval in Advanced NSCLC with PD-L1 TPS ≥ 50%: 3 Weekly Compared to 6 Weekly Dosing

Background: A fixed dose of 200 mg of pembrolizumab every 3 weeks (Q3W) is the standard of care for patients with stage IV non-small cell lung cancer (NSCLC) and PDL1 ≥50%. In April 2020, based on pharmacokinetic modeling without formal comparative studies, the FDA approved 400 mg every 6 weeks (Q6W...

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Hauptverfasser:	Lauren Jones, Rebekah Rittberg, Bonnie Leung, Aria Shokoohi, Alexandra Pender, Selina Wong, Zamzam Al-Hashami, Ying Wang, Cheryl Ho
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2022-11-01
Schriftenreihe:	Current Oncology
Schlagworte:	PDL1 pembrolizumab dosing schedule NSCLC
Online-Zugang:	https://www.mdpi.com/1718-7729/29/11/685
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