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Repurposing antihypertensive drugs for pain disorders: a drug-target mendelian randomization study

ObjectiveAddressing the rising prevalence of pain disorders and limitations of current analgesics, our study explores repurposing antihypertensive drugs for pain management, inspired by the link between hypertension and pain. We leverage a drug-target Mendelian Randomization (MR) approach to explore...

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Principais autores: Kai Du, Ao Li, Chen-Yu Zhang, Shu-Ming Li, Ping Chen
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-08-01
Serier:Frontiers in Pharmacology
Fag:
antihypertensive drug
hypertension
pain management
drug target mendelian randomization
drug repurposing
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2024.1448319/full
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