Chimeric virus-like particles presenting tumour-associated MUC1 epitope result in high titers of specific IgG antibodies in the presence of squalene oil-in-water adjuvant: towards safe cancer immunotherapy

Abstract Background Immunotherapy is emerging as a powerful treatment approach for several types of cancers. Modulating the immune system to specifically target cancer cells while sparing healthy cells, is a very promising approach for safer therapies and increased survival of cancer patients. Tumou...

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Detalhes bibliográficos

Principais autores:	Mirosława Panasiuk, Karolina Zimmer, Anna Czarnota, Magdalena Narajczyk, Grażyna Peszyńska-Sularz, Milena Chraniuk, Lilit Hovhannisyan, Sabina Żołędowska, Dawid Nidzworski, Anna J. Żaczek, Beata Gromadzka
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2022-03-01
Colecção:	Journal of Nanobiotechnology
Assuntos:	Cancer immunotherapy Cancer vaccines VLPs Bioengineered nanostructures MUC1
Acesso em linha:	https://doi.org/10.1186/s12951-022-01357-1
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