Adipose stromal cells bioproducts as cell-free therapies: manufacturing and therapeutic dose determine in vitro functionality

Abstract Background Extracellular vesicles (EV) are considered a cell-free alternative to mesenchymal stromal cell (MSC) therapy. Numerous reports describe the efficacy of EV in conferring immunomodulation and promoting angiogenesis, yet others report these activities to be conveyed in EV-free biopr...

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Hauptverfasser:	Renata Skovronova, Eleonora Scaccia, Sandra Calcat-i-Cervera, Benedetta Bussolati, Timothy O’Brien, Karen Bieback
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2023-10-01
Schriftenreihe:	Journal of Translational Medicine
Schlagworte:	Mesenchymal stromal cells Secretome Immune modulation Angiogenesis
Online-Zugang:	https://doi.org/10.1186/s12967-023-04602-9
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