Lipidomic Analyses Reveal Specific Alterations of Phosphatidylcholine in Dystrophic Mdx Muscle

In Duchenne muscular dystrophy (DMD), lack of dystrophin increases the permeability of myofiber plasma membranes to ions and larger macromolecules, disrupting calcium signaling and leading to progressive muscle wasting. Although the biological origin and meaning are unclear, alterations of phosphati...

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Autors principals:	William J. Valentine, Sherif A. Mostafa, Suzumi M. Tokuoka, Fumie Hamano, Natsuko F. Inagaki, Joel Z. Nordin, Norio Motohashi, Yoshihiro Kita, Yoshitsugu Aoki, Takao Shimizu, Hideo Shindou
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-01-01
Col·lecció:	Frontiers in Physiology
Matèries:	mdx Duchenne phospholipid phosphatidylcholine oleic acid muscular dystrophy
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fphys.2021.698166/full
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