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Enhanced anti-hepatoma effect of a novel curcumin analog C086 via solid dispersion technology

The novel curcumin analog C086, previously identified as an oral novel heat shock protein 90 (Hsp90) inhibitor, was found to exhibit anti-hepatoma activity in vitro and in vivo. However, owing to its limited aqueous solubility, the usage of C086 in the clinical application was restricted. This resea...

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Principais autores: Yanping Deng, Chun Chen, Zhifeng Xiao, Xiuwang Huang, Jianhua Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2020-01-01
coleção:Drug Delivery
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Acesso em linha:http://dx.doi.org/10.1080/10717544.2020.1785051
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