Data mining and safety analysis of dual orexin receptor antagonists (DORAs): a real-world pharmacovigilance study based on the FAERS database

ObjectiveUsing the Food and Drug Administration Adverse Event Reporting System (FAERS) database, four signal detection methods were applied to mine adverse drug events (ADEs) related to use of dual orexin receptor antagonists (DORAs) to provide reference for safe clinical use.Research design and Met...

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Hauptverfasser:	Manxue Jiang, Hao Li, Lingti Kong
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2024-08-01
Schriftenreihe:	Frontiers in Pharmacology
Schlagworte:	dual orexin receptor antagonists (DORAs) insomnia FDA adverse event reporting system adverse drug events data mining
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1436405/full
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