Individual features of the pharmacokinetics of fludarabin phosphate in the treatment of patients with chronic lymphocytic leukemia

Fludarabine is a purine antimetabolite with a pronounced immunosuppressive effect. The inhibitory effect of fludarabine depends on its concentration in blood plasma. In addition, the phenotypic characteristics of patients affect the pharmacokinetic and pharmacodynamic profile of the drug, which nece...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	G. G. Rodionov, I. I. Shantyr, V. B. Vasilyuk, E. A. Kolobova, E. V. Svetkina, M. V. Faraponova, A. B. Verveda, G. I. Syraeva, K. A. Zakharov
Aineistotyyppi:	Artigo
Kieli:	Russo
Julkaistu:	Izdatelstvo OKI 2021-08-01
Sarja:	Качественная клиническая практика
Aiheet:	флударабин в-клеточный хронический лимфолейкоз терапевтический лекарственный мониторинг фармакокинетика персонифицированная медицина
Linkit:	https://www.clinvest.ru/jour/article/view/576
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