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Hematopoietic Stem Cell Aging: Mechanisms, Microenvironment Influences, and Rejuvenation Strategies

Hematopoietic stem cells (HSCs) are essential for lifelong blood production and immune homeostasis. However, aging induces functional declines in HSCs, leading to hematological disorders, immune dysfunction, and increased susceptibility to malignancies. This review explores the biological underpinni...

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Principais autores: Jiaqi Cui, Xincan Li, Bin Liu, Cheng Dong, Yun Chang
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-10-01
Serier:Bioengineering
Fag:
hematopoietic stem cell aging
molecular and cellular mechanisms
microenvironment niche
pluripotent stem cell
rejuvenation strategies
Online adgang:https://www.mdpi.com/2306-5354/12/11/1166
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