OSMR coordinates a self-perpetuating circuit linking chemoresistance and neutrophil-driven immunosuppression in gastric cancer

Chemoresistance and immunosuppression present major challenges in gastric cancer (GC) treatment, with their interplay remaining poorly understood. We identify the Oncostatin M receptor (OSMR) as a central regulator coordinating both chemoresistance and neutrophil-mediated immunosuppression. OSMR was...

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Detalhes bibliográficos

Principais autores:	Dan Wei, Jiang Chen, Feihu Bai, Donglin Li, Jie Liu, Hongjia Dou, Yan Lei, Yongzhen Zhang, Bo Zhang, Ying Pang, Changchun Cao, Tao Yang, Junling Han, Tianyu Cao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-03-01
Colecção:	Neoplasia: An International Journal for Oncology Research
Assuntos:	OSMR Chemoresistance Gastric cancer BMP5 IL31
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S1476558626000084
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