Synthesis of 2,4-Diaminopteridines with Bulky Lipophilic Groups at the 6-Position as Inhibitors of Pneumocystis carinii, Toxoplasma gondii, and Mammalian Dihydrofolate Reductase
Ten previously undescribed 2,4-diamino-6-(2-naphthylamino )methylpteridines with lipophilic chlorine or long-chain alkyl groups on the naphthyl moiety and either hydrogen or a methyl group on N 10 were synthesized from the appropriate 2-naphthylamine or N-methyl-2-naphthylamine by reaction with 2-am...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
De Gruyter
1997-09-01
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| Серии: | Pteridines |
| Предметы: | |
| Online-ссылка: | https://doi.org/10.1515/pteridines.1997.8.3.173 |
| Метки: |
Нет меток, Требуется 1-ая метка записи!
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