Phase separation is regulated by post-translational modifications and participates in the developments of human diseases

Liquid-liquid phase separation (LLPS) of intracellular proteins has emerged as a hot research topic in recent years. Membrane-less and liquid-like condensates provide dense spaces that ensure cells to high efficiently regulate genes transcription and rapidly respond to burst changes from the environ...

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Hlavní autoři:	Weibo Zhang, Zhengfeng Li, Xianju Wang, Ting Sun
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-07-01
Edice:	Heliyon
Témata:	Phase separation Condensates Protein post-translational modifications Protein interactions Cancer
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2405844024100667
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