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Metabolites enhance innate resistance to human Mycobacterium tuberculosis infection

To determine the mechanisms that mediate resistance to Mycobacterium tuberculosis (M. tuberculosis) infection in household contacts (HHCs) of patients with tuberculosis (TB), we followed 452 latent TB infection–negative (LTBI–) HHCs for 2 years. Those who remained LTBI– throughout the study were ide...

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Principais autores: Deepak Tripathi, Kamakshi Prudhula Devalraju, Venkata Sanjeev Kumar Neela, Tanmoy Mukherjee, Padmaja Paidipally, Rajesh Kumar Radhakrishnan, Igor Dozmorov, Abhinav Vankayalapati, Mohammad Soheb Ansari, Varalakshmi Mallidi, Anvesh Kumar Bogam, Karan P. Singh, Buka Samten, Vijaya Lakshmi Valluri, Ramakrishna Vankayalapati
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical investigation 2022-11-01
Series:JCI Insight
Assuntos:
Immunology
Acceso en liña:https://doi.org/10.1172/jci.insight.152357
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