Natural Product Alantolactone Targeting AKR1C1 Suppresses Cell Proliferation and Metastasis in Non-Small-Cell Lung Cancer

Non-small-cell lung cancer (NSCLC) is one of the leading causes of cancer-related deaths, characterized by high invasion and metastasis. Aldo-keto reductase family 1 member C1 (AKR1C1) plays an important role in cancer cell proliferation and metastasis, and has gained attention as an anticancer drug...

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Autores principales:	Zhiwen Fu, Shijun Li, Jinmei Liu, Cong Zhang, Chen Jian, Lulu Wang, Yu Zhang, Chen Shi
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2022-03-01
Colección:	Frontiers in Pharmacology
Materias:	alantolactone AKR1C1 anticancer target identification non-small-cell lung cancer
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fphar.2022.847906/full
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