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Erucin Targets Oncogenic Signaling Pathways in Triple-Negative Breast Cancer: An Integrated Network Pharmacology and In Vitro Study

This study aims to investigate the potential anticancer effects of erucin, an isothiocyanate derived from <i>Eruca sativa</i>, in triple-negative breast cancer (TNBC) by predicting molecular targets and evaluating its in vitro effects on TNBC cell proliferation, apoptosis and cell cycle distribution...

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Principais autores: Humera Banu, Eyad Al Shammari, Husam Qanash, Mitesh Patel, Mohd Adnan, Syed Shahanawaz, Mohammad Idreesh Khan, Malak Yahia Qattan, Syed Amir Ashraf
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-04-01
Serier:Life
Fag:
apoptosis
cell cycle arrest
<i>Eruca sativa</i>
erucin
isothiocyanates
MDA-MB-231 cells
Online adgang:https://www.mdpi.com/2075-1729/16/5/708
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