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Empirical validation of pooled whole genome population re-sequencing in Drosophila melanogaster.

The sequencing of pooled non-barcoded individuals is an inexpensive and efficient means of assessing genome-wide population allele frequencies, yet its accuracy has not been thoroughly tested. We assessed the accuracy of this approach on whole, complex eukaryotic genomes by resequencing pools of lar...

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Библиографические подробности
Главные авторы: Yuan Zhu, Alan O Bergland, Josefa González, Dmitri A Petrov
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2012-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC3406057?pdf=render
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