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The molecular regulatory mechanisms of meiotic arrest and resumption in Oocyte development and maturation

Abstract In human female primordial germ cells, the transition from mitosis to meiosis begins from the fetal stage. In germ cells, meiosis is arrested at the diplotene stage of prophase in meiosis I (MI) after synapsis and recombination of homologous chromosomes, which cannot be segregated. Within t...

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Библиографические подробности
Главные авторы: Zhenle Pei, Ke Deng, Congjian Xu, Shuo Zhang
Формат: Artigo
Язык:Inglês
Опубликовано: BMC 2023-10-01
Серии:Reproductive Biology and Endocrinology
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Online-ссылка:https://doi.org/10.1186/s12958-023-01143-0
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