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Small-Molecule-Driven Hepatocyte Differentiation of Human Pluripotent Stem Cells

The differentiation of pluripotent stem cells to hepatocytes is well established, yet current methods suffer from several drawbacks. These include a lack of definition and reproducibility, which in part stems from continued reliance on recombinant growth factors. This has remained a stumbling block...

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Hlavní autoři: Richard Siller, Sebastian Greenhough, Elena Naumovska, Gareth J. Sullivan
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2015-05-01
Edice:Stem Cell Reports
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2213671115001010
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