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Coregulatory Networks Remodel the Disease-Specific Functions of Orphan Nuclear Receptor TR4

Testicular receptor 4 (TR4, NR2C2) is an orphan nuclear receptor involved in the regulation of metabolism, inflammation, cardiovascular disease, and cancer. Accumulating evidence indicates that TR4 exhibits functional plasticity, exerting protective or pathogenic effects depending on tissue and dise...

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Principais autores: Yunlong Liu, Qing Yu, Shuyuan Cheng, Mengtian Ren, Xiuping Fu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-07-01
Serier:Cells
Fag:
TR4
orphan nuclear receptor
coregulatory networks
transcriptional plasticity
precision medicine
Online adgang:https://www.mdpi.com/2073-4409/15/13/1218
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