Polymorphism Pro64His within galectin-3 has functional consequences at proteome level in thyroid cells

IntroductionThe single nucleotide polymorphism (SNP) rs4644 at codon 64 of galectin-3 (gal-3, gene name: LGALS3), specifying the variant proline (P64) to histidine (H64), is known to affect the protein’s functions and has been associated with the risk of several types of cancer, including differenti...

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Egile Nagusiak:	Roberto Silvestri, Lorenzo Zallocco, Alda Corrado, Maurizio Ronci, Romina Aceto, Benedetta Ricci, Monica Cipollini, Irene Dell’Anno, Chiara De Simone, Giuseppina De Marco, Eleonora Ferrarini, Daniela Beghelli, Maria Rosa Mazzoni, Antonio Lucacchini, Federica Gemignani, Laura Giusti, Stefano Landi
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2024-06-01
Saila:	Frontiers in Genetics
Gaiak:	galectin-3 (gal3) functional polymorphism rs4644 differentiated thyroid carcinoma (DTC) CRISPR/Cas9 proteome papillary thyroid carcinoma (PTC)
Sarrera elektronikoa:	https://www.frontiersin.org/articles/10.3389/fgene.2024.1380495/full
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