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Population Pharmacokinetics of Vancomycin in Chinese ICU Neonates: Initial Dosage Recommendations

The main goal of our study was to characterize the population pharmacokinetics of vancomycin in critically ill Chinese neonates to develop a pharmacokinetic model and investigate factors that have significant influences on the pharmacokinetics of vancomycin in this population. The study population c...

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Principais autores: Zhi-ling Li, Yi-xi Liu, Zheng Jiao, Gang Qiu, Jian-quan Huang, Yu-bo Xiao, Shu-jin Wu, Chen-yu Wang, Wen-juan Hu, Hua-jun Sun
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018-06-01
Serier:Frontiers in Pharmacology
Fag:
neonate
vancomycin
population pharmacokinetic
Monte Carlo simulation
individualized therapy
Online adgang:https://www.frontiersin.org/article/10.3389/fphar.2018.00603/full
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