Design, synthesis, biological evaluation and in silico studies of 2-anilino- 4-(benzimidazol- 1-yl)pyrimidine scaffold as antitumor agents

Abstract In an attempt to rationalize the search for new potential Chemotherapeutic agents, a new series of 2-anilinobenzimidazol derivatives with CDK activity have been synthesized. The newly synthesized compounds have been assessed for their cytotoxic effects and CDK activity. These presented comp...

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Bibliografische gegevens

Hoofdauteurs:	Lamees S. Al-Rasheed, Siddique Akber Ansari, Hanadi H. Asiri, Ahmed H. Bakheit, Abdulrahman A. Al-mehizia, Amsha S. Alsegiani, Hamad M. Alkahtani
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Springer 2025-05-01
Reeks:	Saudi Pharmaceutical Journal
Onderwerpen:	Cancer Benzimidazole CDK Antitumor activity Molecular docking
Online toegang:	https://doi.org/10.1007/s44446-025-00010-w
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