STUDY OF THE THERMAL STABILITY OF BARNASE PROTEIN MUTANTS WITH MOLKERN SOFTWARE

A thermal stability study of several barnase mutants has been carried out by the λ dynamics method. The method has been implemented in the MOLKERN software package. Mutations of amino acids with non-zero charge are chosen for the study, because in this case λ dynamics gives results differing dramati...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	E. S. Fomin, N. A. Alemasov
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2014-12-01
Цуврал:	Вавиловский журнал генетики и селекции
Нөхцлүүд:	barnase molecular dynamics λ dynamics free energy difference protein thermal stability
Онлайн хандалт:	https://vavilov.elpub.ru/jour/article/view/57
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!