The optimal second-line therapy for older adults with type 2 diabetes mellitus: protocol for a systematic review and network meta-analysis using individual participant data (IPD)

Abstract Background Due to increasing life expectancy, almost half of people with type 2 diabetes are aged 65 years or over worldwide. When metformin alone does not control blood sugar, the choice of which second-line therapy to prescribe next is not clear from currently available evidence. The exis...

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Główni autorzy:	Jingya Wang, Krishnarajah Nirantharakumar, Christopher Sainsbury, David J. Moore, Alan Sinclair, G. Neil Thomas, Wasim Hanif, Megha Singh, Luyuan Tan, Zhaonan Wang, Nikita Simms-Williams, Mi Yao, M. Niluka Gunathilaka, Pushpa Singh, Konstantinos Toulis, Apostolos Tsapas, Dyuti Coomar, Malcolm James Price
Format:	Artigo
Język:	Inglês
Wydane:	BMC 2024-06-01
Seria:	Systematic Reviews
Hasła przedmiotowe:	Randomised controlled trials Glucose-lowering agents Glucagon-like peptide-1 agonists Sodium-glucose cotransporter-2 inhibitors Dipeptidyl peptidase-4 inhibitors Biguanide
Dostęp online:	https://doi.org/10.1186/s13643-024-02558-5
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