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The Signature of MicroRNA Dysregulation in Muscle Paralyzed by Spinal Cord Injury Includes Downregulation of MicroRNAs that Target Myostatin Signaling.

Spinal cord injury (SCI) results in muscle atrophy, reduced force generation and an oxidative-to-glycolytic fiber type shift. The mechanisms responsible for these alterations remain incompletely understood. To gain new insights regarding mechanisms involved in deterioration of muscle after SCI, glob...

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Principais autores: Rita De Gasperi, Zachary A Graham, Lauren M Harlow, William A Bauman, Weiping Qin, Christopher P Cardozo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Acceso en liña:https://doi.org/10.1371/journal.pone.0166189
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