Elastomeric Pillar Cages Modulate Actomyosin Contractility of Epithelial Microtissues by Substrate Stiffness and Topography

Cell contractility regulates epithelial tissue geometry development and homeostasis. The underlying mechanobiological regulation circuits are poorly understood and experimentally challenging. We developed an elastomeric pillar cage (EPC) array to quantify cell contractility as a mechanoresponse of e...

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Главные авторы:	Lisann Esser, Ronald Springer, Georg Dreissen, Lukas Lövenich, Jens Konrad, Nico Hampe, Rudolf Merkel, Bernd Hoffmann, Erik Noetzel
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2023-04-01
Серии:	Cells
Предметы:	mechanosensing mechanotransduction cell force measurement cell-matrix adhesion cell-cell adhesion actomyosin
Online-ссылка:	https://www.mdpi.com/2073-4409/12/9/1256
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