Enhancing Synthesis Efficiency in Microbial 1,5-Pentanediol Production Through Transcriptomics-Informed Metabolic Engineering of <i>Escherichia coli</i>

The microbial production of 1,5-pentanediol (1,5-PDO), a versatile platform chemical with extensive industrial applications, remains limited by suboptimal fermentation titers and incomplete understanding of metabolic bottlenecks. To address these challenges, this study employed comparative transcrip...

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Detalhes bibliográficos

Principais autores:	Hongyu Deng, Fei Meng, Yihao Sun, Yang Song, Chunhui Zhao, Xiaonan Wang, Yan Zhang, Ruiming Wang, Ning Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-03-01
Colecção:	Microorganisms
Assuntos:	1,5-pentanediol <i>Escherichia coli</i> transcriptomic analysis metabolic engineering CRISPR/Cas9
Acesso em linha:	https://www.mdpi.com/2076-2607/14/3/715
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