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Differential upregulation of AU-rich element-containing mRNAs in COVID-19

Abstract Background AU-rich elements (AREs) are located in the 3′UTRs of 22% of human mRNAs, including most transiently expressed inflammatory mediators. By default, AREs mark mRNAs for decay and translational inhibition, but this activity can be temporarily inhibited in case of infection to allow t...

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Bibliografiske detaljer
Principais autores: Tala Bakheet, Khalid S. A. Khabar, Edward G. Hitti
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2022-11-01
Serier:Human Genomics
Fag:
Online adgang:https://doi.org/10.1186/s40246-022-00433-9
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