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Endoplasmic Reticulum Stress Is Associated With Autophagy and Cardiomyocyte Remodeling in Experimental and Human Atrial Fibrillation

BackgroundDerailment of proteostasis, the homeostasis of production, function, and breakdown of proteins, contributes importantly to the self‐perpetuating nature of atrial fibrillation (AF), the most common heart rhythm disorder in humans. Autophagy plays an important role in proteostasis by degradi...

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Principais autores: Marit Wiersma, Roelien A. M. Meijering, Xiao‐Yan Qi, Deli Zhang, Tao Liu, Femke Hoogstra‐Berends, Ody C. M. Sibon, Robert H. Henning, Stanley Nattel, Bianca J. J. M. Brundel
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2017-10-01
coleção:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Assuntos:
4PBA
atrial fibrillation
autophagy
Drosophila
drug research
Endoplasmic Reticulum stress
Acesso em linha:https://www.ahajournals.org/doi/10.1161/JAHA.117.006458
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