Slit-Robo signaling supports motor neuron avoidance of the spinal cord midline through DCC antagonism and other mechanisms

Axon pathfinding and neuronal migration are orchestrated by attractive and repulsive guidance cues. In the mouse spinal cord, repulsion from Slit proteins through Robo family receptors and attraction to Netrin-1, mediated by the receptor DCC, control many aspects of neural circuit formation. This in...

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Principais autores:	Kelsey R. Nickerson, Ferass M. Sammoura, Yonghong Zhou, Alexander Jaworski
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2025-04-01
סדרה:	Frontiers in Cell and Developmental Biology
נושאים:	axon guidance neuronal migration spinal cord motor neuron robo signaling crosstalk
גישה מקוונת:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1563403/full
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