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Context-Dependent Role of Mitochondrial Fusion-Fission in Clonal Expansion of mtDNA Mutations.

The accumulation of mutant mitochondrial DNA (mtDNA) molecules in aged cells has been associated with mitochondrial dysfunction, age-related diseases and the ageing process itself. This accumulation has been shown to often occur clonally, where mutant mtDNA grow in number and overpopulate the wild-t...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Zhi Yang Tam, Jan Gruber, Barry Halliwell, Rudiyanto Gunawan
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2015-05-01
Rangatū:PLoS Computational Biology
Urunga tuihono:http://europepmc.org/articles/PMC4440705?pdf=render
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