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Septins tune lipid kinase activity and PI(4,5)P 2 turnover during G-protein–coupled PLC signalling in vivo

In Drosophila photoreceptors, PI(4,5)P 2 synthesis during PLC signalling is regulated by PIP5K and septins. Phosphatidylinositol 4,5-bisphosphate [PI(4,5)P 2 ] hydrolysis by phospholipase C (PLC) is a conserved mechanism of signalling. Given the low abundance of PI(4,5)P 2 , its hydrolysis needs to...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Aastha Kumari, Avishek Ghosh, Sourav Kolay, Padinjat Raghu
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Life Science Alliance LLC 2022-06-01
Rangatū:Life Science Alliance
Urunga tuihono:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202101293
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