Lack of Cardiotoxicity Endpoints in Prospective Trials Involving Chest Radiation Therapy: A Review of Registered, Latter-Phase Studies

BackgroundChest radiation therapy (RT) has been associated with increased cardiac morbidity and mortality in numerous studies including the landmark Darby study published in 2013 demonstrating a linear increase in cardiac mortality with increasing mean heart radiation dose. However, the extent to wh...

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Autors principals:	Rahul N. Prasad, Eric D. Miller, Daniel Addison, Jose G. Bazan
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-02-01
Col·lecció:	Frontiers in Oncology
Matèries:	chest radiation therapy thoracic radiation therapy cardiotoxicity clinical trials major adverse cardiac events breast cancer
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fonc.2022.808531/full
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