Oridonin inhibits inflammation of epithelial cells via dual-targeting of CD31 Keap1 to ameliorate acute lung injury

IntrodcutionAcute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are major causes of COVID-19 mortality. However, drug delivery to lung tissues is impeded by endothelial cell barriers, limiting the efficacy of existing treatments. A prompt and aggressive treatment strategy is there...

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Главные авторы:	Yue Zhao, Hua Jin, Kawai Lei, Li-Ping Bai, Hudan Pan, Caiyan Wang, Xiaoming Zhu, Yanqing Tang, Zhengyang Guo, Jiye Cai, Ting Li
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2023-04-01
Серии:	Frontiers in Immunology
Предметы:	acute lung injury COVID-19 CD31 Keap1 oridonin nanoparticles
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1163397/full
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