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The origin of bladder cancer from mucosal field effects

Summary: Whole-organ mapping was used to study molecular changes in the evolution of bladder cancer from field effects. We identified more than 100 dysregulated pathways, involving immunity, differentiation, and transformation, as initiators of carcinogenesis. Dysregulation of interleukins signified...

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Principais autores: Jolanta Bondaruk, Roman Jaksik, Ziqiao Wang, David Cogdell, Sangkyou Lee, Yujie Chen, Khanh Ngoc Dinh, Tadeusz Majewski, Li Zhang, Shaolong Cao, Feng Tian, Hui Yao, Paweł Kuś, Huiqin Chen, John N. Weinstein, Neema Navai, Colin Dinney, Jianjun Gao, Dan Theodorescu, Christopher Logothetis, Charles C. Guo, Wenyi Wang, David McConkey, Peng Wei, Marek Kimmel, Bogdan Czerniak
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2022-07-01
Serier:iScience
Fag:
Molecular biology
Cell biology
Cancer
Online adgang:http://www.sciencedirect.com/science/article/pii/S2589004222008239
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