Deregulation of secondary metabolism in a histone deacetylase mutant of Penicillium chrysogenum

Abstract The Pc21 g14570 gene of Penicillium chrysogenum encodes an ortholog of a class 2 histone deacetylase termed HdaA which may play a role in epigenetic regulation of secondary metabolism. Deletion of the hdaA gene induces a significant pleiotropic effect on the expression of a set of polyketid...

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Autores principales:	Fernando Guzman‐Chavez, Oleksandr Salo, Marta Samol, Marco Ries, Jeroen Kuipers, Roel A. L. Bovenberg, Rob J. Vreeken, Arnold J. M. Driessen
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2018-10-01
Colección:	MicrobiologyOpen
Materias:	chrysogine crosstalk histone deacetylase naphtha‐γ‐pyrone Penicillium chrysogenum sorbicillinoids
Acceso en línea:	https://doi.org/10.1002/mbo3.598
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